PIA Publications:
Down Syndrome and Alzheimer's Disease

Articles of Interest

January 2017

Bateman, R., Benzinger, T., Berry, S., Clifford, D., Duggan, C., & Fagan, A. et al. (2017). The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model. Alzheimer's & Dementia  2 February 2017.

Lewis, F. & Torgerson, P. (2017). The current and future burden of late-onset dementia in the United Kingdom: Estimates and interventions. Alzheimer's & Dementia, 13(1), 38-44. 

O'Bryant, S., Mielke, M., Rissman, R., Lista, S., Vanderstichele, H., & Zetterberg, H. et al. (2017). Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic. Alzheimer's & Dementia, 13(1), 45-58. 

Leyhe, T., Reynolds, C., Melcher, T., Linnemann, C., Klöppel, S., & Blennow, K. et al. (2017). A common challenge in older adults: Classification, overlap, and therapy of depression and dementia. Alzheimer's & Dementia, 13(1), 59-71. 

Mehta, K. & Yeo, G. (2017). Systematic review of dementia prevalence and incidence in United States race/ethnic populations. Alzheimer's & Dementia, 13(1), 72-83. 

Current Alzheimer Research: Special Issue on Down Syndrome and Alzheimer's Disease: Pathophysiology to Treatment

Hamlett, E., Boger, H., Ledreux, A., Kelley, C., Mufson, E., & Falangola, M. et al. (2015). Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome.CAR, 13(1), 35-52.

Head, E., Lott, I., Wilcock, D., & Lemere, C. (2015). Aging in Down Syndrome and the Development of Alzheimer’s Disease Neuropathology. CAR, 13(1), 18-29.

Iulita, M. & Cuello, A. (2015). The NGF Metabolic Pathway in the CNS and its Dysregulation in Down Syndrome and Alzheimer’s Disease. CAR, 13(1), 53-67.

Kelley, C., Ash, J., Powers, B., Velazquez, R., Alldred, M., & Ikonomovic, M. et al. (2015). Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome. CAR, 13(1), 84-96.

Phillips, C., Fahimi, A., Das, D., Mojabi, F., Ponnusamy, R., & Salehi, A. (2015). Noradrenergic System in Down Syndrome and Alzheimer’s Disease A Target for Therapy. CAR, 13(1), 68-83.

Potter, H., Granic, A., & Caneus, J. (2015). Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer’s Disease. CAR, 13(1), 7-17.

Sabbagh, M. & Edgin, J. (2015). Clinical Assessment of Cognitive Decline in Adults with Down Syndrome. CAR, 13(1), 30-34.

Salehi, A., Ashford, J., & Mufson, E. (2015). Editorial (Thematic Issue: The Link between Alzheimer’s Disease and Down Syndrome. A Historical Perspective). CAR, 13(1), 2-6.

Strupp, B., Powers, B., Velazquez, R., Ash, J., Kelley, C., & Alldred, M. et al. (2015). Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer’s Disease. CAR, 13(1), 97-106.